Suicide Mouse bears a strong resemblance to the Mickey Mouse as first depicted in his early cartoons, as all of his colors are in grayscale and his features match the original cartoon Mickey Mouse, especially when compared to Photo-Negative Mickey. He walks around with his hands tucked behind his back, except for when he is in the Meat Freezer, in which he walks with his arms outstretched.
Whenever Suicide Mouse is active, the TV in the Broadcasting Room will turn on and Suicidemouse.avi will play. Unlike most suits, Suicide Mouse will head directly to the office rather than going back and forth through cams. When he enters The Office, the player must shut off a cam, shut off the power, or hide under the desk, where the last one will give the player a 50/50 chance of surviving. If the player fails to do this in time, Suicide Mouse will attack the player the next time the camera is put down, if they hide, or if they shut off the power.
The pose Suicide Mouse uses when he enters the Meat Freezer is a reference to the suicidemouse.avi mock-up video where Suicide Mouse walks with his hands outstretched.
If the player manages to survive in-game for a long amount of time, Suicide Mouse's full song will play, revealing that it will play the same moaning and screaming from the suicidemouse.avi video in-game. This can be seen in this video.
The television in the Broadcasting Room will remain on until Suicide Mouse leaves the Office in Remastered 1.0.
It is possible for Suicide Mouse to scream up to five times in Remastered 1.0 as seen in this video.